Mid-October around here looks quiet, and that's why it's a good week for plant people. The woods are dropping leaves, and a few plants are doing their best work now: a native shrub opening ribbon-petaled yellow flowers at the very end of the season, a crocus flowering in fall instead of spring, and a prairie coneflower gone dormant, which is the signal its root is ready to dig.
This week's three are a shrub you use for its twigs and bark, a root, and a spice. Each has a research story more complicated than its label, so let's take them one at a time.
Witch Hazel (Twigs & Bark) (Hamamelis virginiana)
American witch hazel is a native deciduous understory shrub (a woodland plant growing beneath taller trees) of woods, forest edges, and stream banks, with smooth grey bark and oval, wavy-edged leaves. It's often called the last flower to bloom in the woods: small, fragrant yellow flowers with four ribbon-like petals open in clusters from October into December, sometimes while leaves are still falling. It's the only witch hazel species that flowers in fall, so that bloom is the easiest way to spot it now.

Where to Find It
Self-Harvest: Witch hazel is native to eastern woodlands, and the easiest ID clue this month is the fall bloom. Use the native species, not the ornamental hybrid cultivars sold for winter color, and be certain of your identification before you cut.
Buy It: Mountain Rose Herbs carries the bark, which is the main part covered here, sold as wild-harvested (the listing is conflicting on organic status, so I won't call it certified organic). Starwest Botanicals sells organic cut-and-sifted leaf (origin United States), and its witch hazel extract is the drugstore-style steam distillate of dormant twigs with 14% alcohol. That's a topical, not a tincture or tea, and it's the same kind of preparation the clinical trials below tested.
Grow Your Own: Strictly Medicinal Seeds sells a certified organically grown potted tree of the Virginian species, hardy in Zones 3–8.
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When to Harvest
Twigs and leaves can be gathered through the growing season. Chestnut School of Herbal Medicine calls them most potent in spring when the sap is running (an herbalist's claim, not a measured one), while ESCOP's monograph for the distillate specifies recently cut, partially dried dormant twigs. So there's no single agreed-on best time.
To take twigs, prune a few handfuls of small branches with sharp shears, cutting just outside the branch collar (the slight ridge where a branch meets its parent) so the shrub can heal. For bark, peel and scrape it; the inner bark is said to hold the most healing compounds.
How to Prepare and Extract
Everything below is a traditional herbalist preparation. None of it is what the research tested.
Decoction (bark and twigs) or infusion (leaves): 1 Tbsp (15 ml) dried material to 1 cup (240 ml) of water, up to 3 times a day, per Chestnut School.
Tincture: Fresh bark and twigs at 1:2 in 80% alcohol, or dried at 1:5 in 40% alcohol.
Topical tonic: Simmer equal parts chopped flowers, leaves, and twigs in distilled water 6–8 hours, adding water to keep them covered; strain and refrigerate.
Vinegar wash: 1 part fresh chopped plant to 2 parts raw apple cider vinegar for 1–6 weeks, used as a wound wash.
Drugstore witch hazel: A steam distillate with about 14% alcohol that Chestnut School calls much weaker than a tincture or tea. Drugs.com says it contains no tannins (astringent plant compounds that tighten tissue), which stay in bark and leaf extracts.
How to Use It
Bruises, sunburn, and skin irritation (traditional): Compresses of the tea or distillate. ESCOP lists bruises, skin irritations, sunburn, insect bites, and external hemorrhoids for the distillate.
Varicose veins and hemorrhoids (traditional): Compresses, per Chestnut School.
Poison ivy (traditional): A strong tea used as a wash.
Face (traditional): Distillate as a toner, or as a compress or steam for acne and eczema.
Gums (traditional): A few drops of tincture along the gumline for bleeding gums.
Sore throat and diarrhea (traditional): Tea has been used internally, but see the safety note before trying that.
Safety
Sources disagree here. Chestnut School lists no known side effects, while Drugs.com says oral use isn't recommended: the tannins can cause nausea, vomiting, or constipation at extract doses around 1 g, possible liver damage if tannins are absorbed in quantity, and safety of leaf or twig teas is unknown. I always tend to lean towards caution when I see warnings like this- especially on internal use. There is usually another herb better suited. Allergic contact dermatitis (a skin rash) has been reported, and cross-sensitivity with the daisy family is possible. Pregnancy and nursing data are lacking.
Other safety measures may be appropriate for you. Always consult a physician.
What the Research Says
The evidence is modest, and none of it is on a home tea, decoction, or tincture. The research covers a commercial twig distillate and a lab extract of the bark.
A 2022 lab study in the International Journal of Molecular Sciences applied a standardized bark extract to cultured human skin cells (keratinocytes) exposed to eczema-like inflammatory signals. The extract reduced release of several inflammation messengers, and the whole extract worked better than its pure compound hamamelitannin alone. It's cells in a dish only, and two authors are affiliated with a company that sells witch hazel products.
Two clinical trials tested the twig distillate. In a double-blind trial of 72 adults with atopic eczema, hamamelis cream, its plain cream base (the vehicle), and 0.5% hydrocortisone all eased itch, redness, and scaling, but hamamelis did not differ meaningfully from the base. In a UV-redness test on 40 volunteers, hydrocortisone worked best, and only one hamamelis lotion beat its vehicle, at a single UV dose.
Narrow-Leaved Purple Coneflower Root (Echinacea angustifolia)
We covered echinacea back in June with the flowers and root together. This time it's the root alone, because fall is when it's dug, and I went looking for fresh research on it.
Echinacea angustifolia is native to the Great Plains, in drier country like western Kansas, Nebraska, and the Dakotas. It's a perennial about two feet tall, hardy to Zone 3, with pink-to-purple ray petals (the "petals" around the cone) shorter than those of E. pallida. The root contains isobutylamide, a tongue-numbing compound said to run higher here than in E. pallida. Fall is the digging window, once the plant goes dormant.

Where to Find It
Self-Harvest: Digging a taproot is a big ask of a plant, and I haven't researched how wild stands hold up to it, so look into that before digging from the wild. NC State also warns that improper harvest and storage, especially of wild-harvested material, greatly reduces bioactive content.
Buy It: Starwest Botanicals sells organic cut-and-sifted E. angustifolia root (origin United States) and an organic root powder, handy if you'd rather fill capsules or stir it into something. Mountain Rose Herbs carries organic dried root too; its listing doesn't say cut or whole. Check the Latin name on any echinacea product, since the species matters here.
Grow Your Own: Mountain Rose Herbs sells organic seed, a 50-seed pack of a Saskatchewan-origin type. The listing says to sow in fall or early spring, or to give the seed 30–90 days of cold, moist stratification (a chilling period that mimics winter) first. It likes full sun and alkaline soil. Roots take a few seasons: the second to fourth growing season, depending on the source.
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When to Harvest
Dig roots in fall, after the plant goes dormant: NC State says usually after the second to fourth growing season, K-State says the second or third year. Work carefully to avoid breaking the taproot (a spading fork suits a small planting). The top 6–12 inches come up easily, the whole root is hard to get, and remnants can resprout. Keep what you dig in the shade.
How to Prepare and Extract
Washing and drying: Wash promptly and process quickly to limit oxidation (loss of active compounds from air exposure). Richo Cech's method, relayed by NC State: low heat and high airflow on non-aluminum screens, about a day at 70°F, then about 110°F until the roots snap. Store in light-proof containers, cool, dark, and dry, up to about a year.
Tea: The European Medicines Agency (EMA) monograph for E. angustifolia root gives 1 g in 150 ml of water, infused or decocted at least 10 minutes, up to 3 times a day.
Powder: 500 mg up to 3 times a day.
Tincture and liquid extract: A 1:5 tincture in 45% ethanol, 1–2 ml up to 3 times a day, or a 1:1 liquid extract in 45% ethanol, 0.25–1 ml up to 3 times a day.
Fresh-root tincture: One herbalism text describes fresh root in 80-proof alcohol for 4–6 weeks, but doesn't name the species, so treat it as general.
How to Use It
Common cold (traditional use): The European Medicines Agency registers E. angustifolia root as a traditional herbal medicine for supportive treatment of the common cold, based on long-standing use only, started at the first signs. If symptoms persist beyond 10 days, see a doctor. It isn't recommended under age 12. Health Canada does not allow products to claim they prevent colds or flu.
Safety
Avoid it if you're allergic to the daisy family (Asteraceae). Rare anaphylaxis (a severe allergic reaction) is possible, especially in people with atopy (a tendency toward allergies). The European Medicines Agency doesn't recommend it for progressive systemic or immune diseases such as tuberculosis, multiple sclerosis, HIV/AIDS, collagenoses, or white blood cell disorders. NCCIH says allergic reactions may be severe, usual side effects are digestive, and people on immunosuppressants or liver-metabolized medications, and those who are pregnant, should talk to a provider first.
Other safety measures may be appropriate for you. Always consult a physician.
What the Research Says
The best direct trial of the root was negative. If you're wondering whether echinacea root stops a cold, this study found it didn't, and the traditional-use registration rests on long history, not on this kind of proof.
In a 2005 New England Journal of Medicine trial, researchers gave 437 volunteers one of three E. angustifolia root extracts (made with supercritical CO2, 60% ethanol, or 20% ethanol, each with a different chemical profile) or a placebo. Some started a week before being infected with rhinovirus type 39 (a common cold virus), and some started on the day of infection. Of the 399 analyzed over five days, there was no statistically significant effect on infection rate, symptom severity, nasal secretions, or viral load. The authors concluded the root extracts had no clinically significant effect.
That's one trial of three specific extracts under experimental infection, so it doesn't settle every question. NCCIH says echinacea may slightly lower the chance of catching a cold and that it's unclear whether it shortens one, but that statement doesn't specify species or plant part.
Saffron (Crocus sativus)
Saffron is the dried stigmas, the three red threads inside each saffron crocus flower. It's grown as a crop in many countries, and the fall bloom is the story now: in Pennsylvania flowers open from late October through December, in Vermont late October through November. It's hardy in USDA Zones 6–9 and planted as corms (bulb-like underground storage organs) in late summer to early fall.
If you plan on growing this, do yourself a favor and use a raised bed that’s waist height or so. My first year growing it I planted it in the ground and I did not enjoy harvesting it! Chipmunks also will hunt down your bulbs, so a nice mesh cover is a great idea.

Where to Find It
Buy It: Mountain Rose Herbs sells organic saffron threads grown in the Pacific Northwest by Cyrus Saffron, in 1 g and 5 g sizes. Saffron is sometimes adulterated, including with safflower, so a seller you trust matters more here than with most herbs.
Grow Your Own: Corms are the normal way to grow saffron. Territorial Seed Company sells fall-planted corms in packs of 10, 20, or 30 for Zones 6–9, shipped within the contiguous US, with instructions to plant on arrival 4 inches deep and 6 inches apart. White Flower Farm sells 25 bulbs, also for Zones 6–9.
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When to Harvest
Pick flowers in the morning, when fully elongated and just starting to open, generally within two or three days of opening. Pick every other day early in the bloom and daily at the peak, after dew or rain has dried. Cut each flower at its base and leave the leaves on the plant, since they feed next year's corms. Separate the stigmas from petals and stamens as soon as you can, because flowers wilt within a day. If you can't get to it, refrigerate them on a paper towel on a tray.
How to Prepare and Extract
Drying: Penn State Extension says to air-dry stigmas indoors on dry paper towel for 1–2 days, or oven-dry at 130°F for 60 minutes, 170°F for 25 minutes, or 210°F for 7–10 minutes. Penn State cites University of Vermont research that 210°F for 7–10 minutes gives the highest flavor. Gentle warmth only until the threads snap cleanly; high heat scorches them.
Storage: Keep in an airtight glass or metal container, cool, dark, and away from heat and light. Properly dried saffron keeps a year or more.
Yield: About 4,000 blossoms make an ounce, which works out to roughly 140 flowers per gram.
Tea and tincture ratios for saffron weren't verified, so I'm leaving them out. The research below used measured daily doses, not kitchen preparations.
How to Use It
Cooking: The threads are mainly a culinary spice, and that's the everyday use.
Mood (studied, not a kitchen use): The trials below used about 30 mg a day of saffron for 6–12 weeks. Drugs.com notes clinical studies used 20–400 mg a day, with up to 1.5 g a day considered safe, so a pinch in a recipe is not a studied dose. If you're dealing with depression, please work with a clinician rather than self-treating with spice.
Safety
Doses of about 5 g have caused severe effects including bleeding, purpura (purple skin spots), and low platelets, and 10–20 g may be fatal. Avoid saffron in pregnancy (5 g or more has uterine-stimulating effects, and lactation safety isn't established) and with bleeding disorders. A theoretical interaction with antiplatelet medicines exists, and bleeding was reported with rivaroxaban in one case report. Nausea, vomiting, headache, and allergy are possible. Buy from a trusted source because of adulteration.
Other safety measures may be appropriate for you. Always consult a physician.
What the Research Says
Saffron has real human research behind it for mild to moderate depression, but the evidence is thinner than it sounds: small, short trials, all from one country.
A 2018 meta-analysis (a study that pools results from several trials) in Neuropsychiatric Disease and Treatment combined seven randomized controlled trials, all from Iran: three against placebo and four against standard antidepressants such as fluoxetine, imipramine, and citalopram. Most used 30 mg a day for 6–12 weeks, one used 100 mg, and one tested petal rather than stigma. Against placebo, saffron scored substantially better (standardized mean difference −1.22), though the results varied a lot between trials. Against antidepressants it performed about equally, and there were no serious adverse events. Common effects were appetite change (18.6%), anxiety (12.4%), headache, and nausea (about 11% each). The authors note the small number of trials, possible patient overlap, and unknown long-term safety.
From the Garden Gate
Plant garlic and spring bulbs before the ground freezes. Fall planting gives them the winter chill they need.
Leave some seed heads standing. Birds will use them through winter.
Until next time...
Each of this week's three comes with a catch: a witch hazel that's mostly studied as a drugstore distillate, an echinacea root with a negative trial, and a spice whose research uses doses far above a pinch. That's worth remembering the next time you read a label. If you try anything from this issue, start with the easiest one and go look for a witch hazel in bloom. Come tell us what you're working on and ask questions in the Facebook group: https://www.facebook.com/share/g/1Fsj7TcsFN/
See you in the group!
—Dana
About the editor: Dana is an herbalist, forager and grower who puts plants first for her family's health. She enjoys teaching and learning — and is always up for a conversation about plants of all kinds. Dana also owns the Facebook community: Growing and Harvesting Medicinal Herbs & Teas.

